Summary
Overview
Work History
Education
Skills
Timeline
Generic

SHUWEN CHANG

ASSOCIATE INVESTIGATOR
1068 Xueyuan Avenue, Shenzhen University Town, Shenzhen, P.R.China

Summary

I am a neuroscientist and enjoy using real time methodology to visualize synaptic activity. In combination of super-resolution light microscopy and electrophysiology, the ultimate goal is to understand how synaptic proteins work to modulate synapse plasticity.

Overview

10
10
years of professional experience

Work History

Associate Investigator

Shenzhen Institute Of Advanced Technology
11.2020 - Current
  • Study how intrinsically disordered region driven liquid-liquid phase separation regulates postsynaptic assembly.
  • Investigate how high-order inositol phosphate in regulation short-term synaptic plasticity.
  • Supervise graduate students and junior researchers, providing guidance on research methods, project management, and professional development opportunities.

Postdoc Research

The Hospital For Sick Children
01.2019 - 12.2020
  • Investigated how IQ motif of P/Q type Ca2+ channel regulates Ca2+ dependent facilitation.
  • Established optogentic tool to modulate phosphoinositol at presynaptic active zone.

Postdoc Research

Charite Universitatsmedizin Berlin, Neurocure
01.2014 - 03.2017
  • Investigated molecular mechanism underlying dynamic synaptic vesicle docking using flash-and-freeze and electron microscopy.

Education

Ph.D. - Neuroscience

Georg-August-Universität Göttingen
Göttingen, Germany
04.2001 -

Master of Science - Biochemistry And Molecular Biology

National Yang-Ming University
Taipei, Taiwan
06.2007

Bachelor of Science - Biology

National Cheng-Kung University
Tainan, Taiwan
06.2005

Skills

  • Synaptic electrophysiology
  • Super resolution light microscopy
  • High pressure freezing
  • Electron microscopy
  • Timeline

    Associate Investigator

    Shenzhen Institute Of Advanced Technology
    11.2020 - Current

    Postdoc Research

    The Hospital For Sick Children
    01.2019 - 12.2020

    Postdoc Research

    Charite Universitatsmedizin Berlin, Neurocure
    01.2014 - 03.2017

    Ph.D. - Neuroscience

    Georg-August-Universität Göttingen
    04.2001 -

    Master of Science - Biochemistry And Molecular Biology

    National Yang-Ming University

    Bachelor of Science - Biology

    National Cheng-Kung University
    SHUWEN CHANGASSOCIATE INVESTIGATOR